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Comments: Patients with undetectable VL and high CD4 counts (> 500 ?l -1 ) in the absence of ART during follow-up have a low risk of progressing HIV infection.

In order to avoid side effects of ARVs and in the absence of any indication for initiation of ART, except for the presence of HIV infection, treatment may be delayed until the indication becomes available.

A prerequisite for making a decision is the presence of regular dispensary observation of the patient with the possibility of studying CD4 and VL. At the same time, it should be explained to the patient that the absence of therapy entails an increase in the level of systemic inflammation and an increase in the risks of concomitant diseases, even with “elite control”. recommended to physicians responsible for the observation of HIV-infected people before starting ART to conduct a survey of patients in the scope of dispensary observation . [3,5,37,57,108,109,110,111,112] (1A) Comments: The examination is carried out to obtain baseline data that will allow assessing the safety and efficacy of the therapy. According to the results Buy online - Viral Symmetrel (Amantadine) Anti 100mg of clinical laboratory and instrumental studies, the state of the main organs and systems of the body (CNS, hematopoiesis, kidneys, liver, lungs, CVS), the presence of concomitant and secondary infections (CVH B and C, tuberculosis, toxoplasmosis) and conditions (pregnancy), as well as viral replication activity (VN) and severity of immunosuppression (CD4 level).

The scope of required research is presented in Section 2.3.

recommended that physicians responsible for the care of HIV-infected patients prepare the patient psychologically before starting ART [89,90,91] (2A) Comments: Treatment is conducted on a voluntary basis and involves the active participation of the patient, therefore, the most important component of the success of ART is the psychological preparation of the patient, Buy Copegus (Ribavirin) 100mg online - Anti Viral an integral part of which is counseling on adherence to treatment, its expected effectiveness, contraindications and possible complications of the planned therapy. Women of childbearing age are informed about the possible impact of the treatment on the course of pregnancy and fetal development. recommended that physicians responsible for the care of HIV-infected individuals obtain written “informed consent” from the patient, certified by the attending

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  • , before prescribing ART (see Appendix D2) [89] (2A) Comments: The signing of the "Informed Consent for ART" is the logical conclusion of the preparation (including psychological) of the patient for ART and includes a mandatory discussion with the patient of all the provisions of the informed consent. recommended that clinicians responsible for the care of HIV-infected individuals should test for genotypic resistance prior to initiating ART, preferably as soon as an HIV diagnosis is made; or before starting ART [113] (5S): all patients in regions with a prevalence of resistance greater than 10% who are at high risk of primary NNRTI resistance due to widespread use of this group of drugs in the region Characteristics of ARVs and ART regimens are presented in Appendix D1. recommended that physicians responsible for monitoring HIV-infected patients choose the optimal ART regimen for a given patient, taking into account possible contraindications to prescribing individual ARVs and risk factors for their use [3,4,37,97,114,115,116] (2A) .

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