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Phases: progression against the background of the absence of ART, against the background of ART; remission (spontaneous, after ART, during ART).

Weight loss of more than 10%, unexplained diarrhea or fever for more than a month, repeated persistent viral, bacterial, fungal, protozoal lesions of internal organs, localized Kaposi's sarcoma, recurrent or disseminated herpes zoster. Phases: Buy Kamagra Effervescent (Sildenafil Citrate) 100mg online - Erectile Dysfunction progression against the background of the absence of ART, against the background of ART; remission (spontaneous, after ART, during ART).

Generalized viral, bacterial, mycobacterial, fungal, protozoal, parasitic diseases, including: candidiasis of the esophagus, bronchi, trachea, lungs; pneumocystis pneumonia; malignant tumors; damage to the central nervous system. Phases: progression against the background of the absence of ART, against the background of ART; remission (spontaneous, after ART, during ART). Characteristics of the stages of HIV infection Stage 1 - stage of incubation - the period from the moment of infection to the appearance of the body's reaction in the form of clinical manifestations of "acute infection" and / or the production of antibodies. Duration usually ranges from 4 weeks to 3 months, but in isolated cases it can increase up to 1 year. During this period, active reproduction of HIV occurs in the absence of clinical manifestations of the disease, antibodies to HIV may not be detected. The diagnosis of HIV infection at this stage is made on the basis of epidemiological data; it can be laboratory confirmed by the detection of HIV, its antigens, nucleic acids in the patient's blood. During this period, active HIV replication continues and the body's primary response to the introduction of the pathogen appears in the form of clinical symptoms and / or antibody production.

It is believed that the patient may be in the stage of primary manifestations within 12 months after seroconversion (the appearance of antibodies to HIV). The stage of primary manifestations can proceed in several forms. Stage 2A - asymptomatic , when there are no clinical manifestations of HIV infection or opportunistic diseases developing against the background of immunodeficiency.

The body's response to the introduction of HIV is manifested in this case only by the production of antibodies. Stage 2B - Acute HIV infection without secondary disease may present with a variety of clinical symptoms.

Most often, this is an increase in lymph nodes, fever, pharyngitis, rashes (urticarial, papular, petechial) on the skin and mucous membranes.

There may be an increase in the liver, spleen, the appearance of diarrhea.

Sometimes aseptic meningitis develops, which is characterized by a meningeal syndrome with an increase in CSF pressure in the absence of its visual and cytological changes.

Due to the fact that the clinical picture of acute HIV infection often resembles measles, rubella, infectious mononucleosis, it is called "mononucleosis-like syndrome", "rubella-like syndrome". The similarity with infectious mononucleosis enhances the appearance in the blood of patients with acute HIV infection of wide plasma lymphocytes (mononuclear cells).

A mononucleosis-like or rubella-like picture is observed in 15–30% of patients with acute HIV infection; most develop 1-2 of the above symptoms in any combination.

In some patients with HIV infection, autoimmune lesions may occur.

In general, the acute stage of HIV infection is recorded in 50–90% of infected individuals in the first 3 months.

The onset of the acute infection period usually precedes seroconversion, therefore, when the first clinical symptoms appear, antibodies to HIV may not be detected in the patient's blood serum.