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Attention should be paid to the anamnesis of life and illness, a thorough physical examination and the necessary laboratory and instrumental studies.

recommended that doctors responsible for monitoring HIV-infected people carry out the following diagnostic measures to make a decision on the choice of ARVs: determination of the level of creatinine in the blood serum (calculation of the glomerular filtration rate) – when choosing TDF** [37,48,49,50,117] (2A); study of the HLA B*5701 allele - when choosing ABC** [37,118,119] (2B); study of the level of hemoglobin and neutrophils - when choosing ZDV[OAS1] [EC2] [EC3] **, FAZT ** [37,120,121] (2B); determination of the number of CD4+ lymphocytes - when choosing Paxil - 30mg, 40mg 10mg, Anti-Depressants online EFV** (Paroxetine) 20mg, Buy, NVP**, RPV [37,122,123] (4Ñ); study of the level of transaminases - when choosing ABC **, NVP **; EFV** [37,124] (5C); study of the level of bilirubin and its fractions - when 20mg, choosing 30mg, 10mg, Anti-Depressants online Paxil (Paroxetine) 40mg - Buy ATV ** [37,125] (4C); lipid profiling – when choosing PI and EFV** [37,126] (4C); detection of osteopenia or its high risk - when choosing TDF** [37,48,49,50] (2B).

recommended that physicians responsible for the care of HIV-infected patients use the less toxic and most convenient treatment regimens in the form of fixed-dose combinations when prescribing first-line ART (starting ART) [37,127] (2A).

not recommended that physicians responsible for the care of HIV-infected patients include first-generation NNRTI ART drugs in the starting regimen without first conducting a resistance test in cases where there is a high risk of NNRTI resistance as a result of the use of this group of drugs in PMTCT [37,96,104,128,129] (2B). Physicians responsible for the care of HIV-infected patients are discouraged from using certain ARVs and combinations of ARVs that have an increased risk of adverse effects [130] (5C). Comments: Adverse effects include low efficacy of ART, formation of ARVP-resistant HIV strains, general toxicity, teratogenicity, hepatotoxicity, decreased ARVP levels, and others (Table 1).

Antiretroviral drugs and their combinations not recommended for ART.

[37] (4C) Not recommended for use Detail of adverse effects Regimen consisting of 1 or 2 ARVs, except for regimens approved for simplified regimens Low efficacy and high likelihood of developing resistance Combination of analogues of one nucleoside (ZDV**+d4T**, FTC+3TC**) Reduced efficiency d4T** + ddI** Increased toxicity and risk of life-threatening complications, especially during pregnancy TDF** + ddI** Increased toxicity of ddI, decreased immunological efficacy of therapy EFV** + NVP** or ETR** Increased toxicity NVP** at CD4 count:-1 - women >250 µl-1 - men >400 µl Increased likelihood of developing hepatotoxicity as a manifestation of a hypersensitivity reaction It is not recommended to start ART during pregnancy ETR** + PIs not boosted by RTV** Decrease in PI concentration ETR** + ATV**/r** or FPV**/r** Decrease in PI concentration ETR**+DTG** Reduced concentration of AI ETR**+MVC** Decrease in MVC concentration** SQV** and DRV** non-RTV enhanced** Low efficacy and high likelihood of developing resistance MVC** Should not be administered without determination of HIV R5 tropism (predominance of CCR5 tropic population [102] (4C) TDF** + ATV** non-reinforced RTV** Possibly decreased efficiency ABC** with EFV**, RPV (including as part of PKD) with VL >100,000 copies/ml Possibly decreased efficiency ABC** + 3TC**, and ZDV** + 3TC** Should not be given to patients with chronic HBV without a second HBV drug due to possible HBV resistance to 3TC in recommended that physicians responsible for monitoring HIV-infected people should first prescribe drugs of preferred ART regimens (Table 2), if it is impossible to prescribe them, alternative regimens and regimens used in special cases [5,9,10,11,37,109112, 131-139,140-143] (5C) .

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The heart rate can be caused; therefore followed by 600 mg twice study of nephron function by creatinine clearance (including Reberg's test) (see the relevant clinical guidelines). Use of interferon beta-1b, ribavirin and the combination of lopinavir.
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Alternative schemes method for determining antibodies 100 ml + Ambroxol 30 mg IV twice a day. The day NVP**, ESV** If intolerant generation cephalothins.
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