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1177n (as amended by the Order of the Ministry of Health of the Russian Federation of August 10, 2015 No.
549n), when applying for medical help to a medical organization providing medical care in a hospital, the patient signs general informed consent to medical interventions carried out in a medical institution, included in the List of certain types of medical interventions (determined by order of the Ministry of Health and Social Development of Russia dated April 23, 2012 No.
Paragraph 9 of this order approved laboratory methods of examination, including clinical, biochemical, bacteriological, virological, immunological.
In turn, according to the Order of the Ministry of Health of the Russian Federation of February 21, 2000 No. 64 "On Approval of the Nomenclature of Clinical Laboratory Tests", the nomenclature of clinical laboratory tests defines immunoserology (clause 9.2.3.) and microbiological methods for identifying viruses (clause 9.2. 4.), which allows for ELISA and PCR diagnostics of HIV infection when signing informed consent for medical intervention.
The tasks of a laboratory examination when registering for a dispensary for HIV infection include: confirmation of the diagnosis of HIV infection; determination of the degree of immunosuppression (by absolute and percentage of CD4 and CD8); identification of indications for chemoprophylaxis of secondary diseases (according to the absolute and percentage of CD4); identification of vital indications for an urgent start of ART; identification of secondary diseases, determination of their severity and the need for treatment; identifying comorbidities, determining their severity and the need for treatment.
Nonspecific laboratory signs of HIV infection are: decrease in the number of lymphocytes, especially CD4; an increase in the number of CD8; inversion of the CD4 / CD8 ratio (decrease to Buy Tritace (Ramipril) 2,5mg, 1,25mg, 5mg, 10mg online - Blood Pressure less than 1); an increase in the number of immunoglobulins, mainly due to IgG; manifestations of cytopenic syndrome (anemia, leukopenia, thrombocytopenia).
recommended to carry out the following laboratory diagnostic measures for all patients when registering for a dispensary to clarify the stage of the disease: CD4 study [32-37] (2A); CD8 study [32-37] (4C); quantitative determination of HIV-1 RNA in blood plasma by PCR [32-39] (2A); general (clinical) blood test, detailed [41] (4Ñ); general (clinical) urinalysis [42] (4C); general therapeutic biochemical blood test [42] (4Ñ); blood test to assess lipid metabolism disorders, biochemical [42] (4C); recommended that doctors responsible for monitoring HIV-infected people take the following diagnostic measures if it is necessary to make a decision to start ART on an urgent basis: determination of the clinical stage of the disease according to the Republic of Kazakhstan, 2006 [37, 161] (2A); CD4 study [37, 161] (2A); study of the level of chorionic gonadotropin in the blood [94, 200, 201] (1A).