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Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein.
(1) Option 1: Spilled liquid should be covered with chlorine disinfectant wipes (containing 5000 mg/l effective chlorine) and carefully removed, then the surfaces of the object should be wiped twice with chlorine disinfectant wipes (containing 500 mg/l effective chlorine); Wuhan [EB/ OL ], (in Chinese) (2020-01-27)(2020-03-15] .
http://www.chinacdc.cn/yw_9324/202001 /t20200127_211469.html _ MEDICAL CONSULTING - with SARS-CoV-2 neutralizing antibody titers >1:320 (if such testing has been performed) 1.1 General one Identification of adverse drug reactions 1.2 Rehabilitation therapy 02/28/2020 Doi: 10.1001/jama.2020.3072 PubMedGoogle Scholar article.
- If a mother wants to breastfeed, she should wear a face mask and practice hand hygiene before each feed. > The route of transmission of the infection is airborne (when coughing, sneezing, talking), airborne and contact routes. There is evidence of the possibility of fecal-oral transmission of the SARS-CoV-2 virus within 2 weeks from 10% of those who have been ill with a negative nasopharyngeal test. (2) For patients with a history of autoimmune disease or selective IgA deficiency , the use of convalescent plasma should be evaluated by physicians with caution. 5 Management of patients with repeated positive reaction after discharge (1) The first choice for patients with respiratory problems is the V - V mode .
Mode V - A should not be the first option precisely because of the possible problems with blood circulation.
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• cyanosis and shortness of breath, determined by visual examination, swelling of the wings of the nose in children of the first year of life; • ATTENTION! 4.1 General • Early stage: 100 mmHg Exercise therapy, physiotherapy. > To oblige citizens who live together during the period of isolation with sick persons and persons who visited territories where cases of a new coronavirus infection have been registered, with citizens in respect of whom decisions of sanitary doctors on isolation have been adopted, to ensure self-isolation at home for a period of 14 days, or for the period specified in the decisions of sanitary doctors. • It is better to use high-flow oxygen therapy through nasal cannulas than CPAP therapy.
??Deep-slow breathing: during inspiration, the patient should try his best to actively move the diaphragm. Breathing should be as deep and slow as possible to avoid the decrease in breathing efficiency caused by rapid, shallow breathing. Compared to thoracic breathing, this type of breathing requires less muscle strength, but has better tidal volume and ventilation-perfusion index values, which can be used to control breathing during dyspnea. > Studies of similar viruses have shown a higher risk of severe disease in pregnant women.
(2) Place medical waste in a double-layer medical waste bag, close the bag tightly with zip ties to form an S -shape, and spray the bag with a disinfectant containing 1000 mg/L of chlorine; • at the prehospital stage, inform all potentially contact medical personnel about her arrival.